Human Gene LRRC7 (ENST00000651989.2_8) from GENCODE V47lift37
  Description: leucine rich repeat containing 7, transcript variant 11 (from RefSeq NM_001370785.2)
Gencode Transcript: ENST00000651989.2_8
Gencode Gene: ENSG00000033122.21_19
Transcript (Including UTRs)
   Position: hg19 chr1:70,033,605-70,610,047 Size: 576,443 Total Exon Count: 27 Strand: +
Coding Region
   Position: hg19 chr1:70,034,323-70,587,570 Size: 553,248 Coding Exon Count: 27 

Page IndexSequence and LinksPrimersMalaCardsCTDGene Alleles
Microarray ExpressionRNA StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Methods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr1:70,033,605-70,610,047)mRNA (may differ from genome)Protein (1575 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCMalacardsMGIOMIMPubMedUniProtKB
WikipediaBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  MalaCards Disease Associations
  MalaCards Gene Search: LRRC7
Diseases sorted by gene-association score: dental pulp necrosis (9), dental pulp disease (4)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -311.50718-0.434 Picture PostScript Text
3' UTR -6422.2022477-0.286 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGDEnsembl   
      
      

-  Descriptions from all associated GenBank mRNAs
  AK294206 - Homo sapiens cDNA FLJ54846 complete cds, highly similar to Leucine-rich repeat-containing protein 7.
AF498274 - Homo sapiens densin-180 like protein mRNA, complete cds.
AF434715 - Homo sapiens densin-180 mRNA, complete cds.
BC128989 - Homo sapiens leucine rich repeat containing 7, mRNA (cDNA clone MGC:144918 IMAGE:8381584), complete cds.
CR749629 - Homo sapiens mRNA; cDNA DKFZp686I1147 (from clone DKFZp686I1147).
BC080568 - Homo sapiens cDNA clone IMAGE:6537117.
AB037786 - Homo sapiens mRNA for KIAA1365 protein, partial cds.
AX786956 - Sequence 1 from Patent WO03006493.
BX648943 - Homo sapiens mRNA; cDNA DKFZp686O2344 (from clone DKFZp686O2344).
JD114484 - Sequence 95508 from Patent EP1572962.
JD563015 - Sequence 544039 from Patent EP1572962.
JD504078 - Sequence 485102 from Patent EP1572962.
JD093937 - Sequence 74961 from Patent EP1572962.
JD322480 - Sequence 303504 from Patent EP1572962.
JD105680 - Sequence 86704 from Patent EP1572962.
JD376313 - Sequence 357337 from Patent EP1572962.
JD158985 - Sequence 140009 from Patent EP1572962.
JD158986 - Sequence 140010 from Patent EP1572962.
JD275739 - Sequence 256763 from Patent EP1572962.
JD275740 - Sequence 256764 from Patent EP1572962.
JD208779 - Sequence 189803 from Patent EP1572962.
JD208780 - Sequence 189804 from Patent EP1572962.
JD264173 - Sequence 245197 from Patent EP1572962.
JD438879 - Sequence 419903 from Patent EP1572962.
JD112151 - Sequence 93175 from Patent EP1572962.
JD096697 - Sequence 77721 from Patent EP1572962.
HZ483266 - JP 2015535430-A/3772: TERMINALLY MODIFIED RNA.
HZ793197 - JP 2016504050-A/4942: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
JC515929 - Sequence 6182 from Patent WO2014113089.
LQ073517 - Sequence 3841 from Patent EP2964234.
HZ483258 - JP 2015535430-A/3764: TERMINALLY MODIFIED RNA.
HZ793189 - JP 2016504050-A/4934: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
JC515921 - Sequence 6174 from Patent WO2014113089.
LQ073509 - Sequence 3833 from Patent EP2964234.
JD067941 - Sequence 48965 from Patent EP1572962.
JD153145 - Sequence 134169 from Patent EP1572962.
JD285545 - Sequence 266569 from Patent EP1572962.
JD505673 - Sequence 486697 from Patent EP1572962.
JD106969 - Sequence 87993 from Patent EP1572962.
JD414843 - Sequence 395867 from Patent EP1572962.
JD379692 - Sequence 360716 from Patent EP1572962.
BC037323 - Homo sapiens cDNA clone IMAGE:5261489.
BX648061 - Homo sapiens mRNA; cDNA DKFZp686I24203 (from clone DKFZp686I24203).
MA647018 - JP 2017113010-A/4942: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
MA734902 - JP 2017140048-A/3772: TERMINALLY MODIFIED RNA.
MA647010 - JP 2017113010-A/4934: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
MA734894 - JP 2017140048-A/3764: TERMINALLY MODIFIED RNA.
MA804071 - JP 2018183181-A/4942: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
MA804063 - JP 2018183181-A/4934: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.

-  Other Names for This Gene
  Alternate Gene Symbols: A0A494C1A4, A0A494C1A4_HUMAN, ENST00000651989.1, LRRC7 , NM_001370785, uc328trz.1, uc328trz.2
UCSC ID: ENST00000651989.2_8
RefSeq Accession: NM_001370785.2

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.