Human Gene KIAA0232 (ENST00000307659.6_4) from GENCODE V47lift37

JavaScript is disabled in your web browser

You must have JavaScript enabled in your web browser to use the Genome Browser

Description: KIAA0232, transcript variant 1 (from RefSeq NM_014743.3)
Gencode Transcript: ENST00000307659.6_4
Gencode Gene: ENSG00000170871.12_11
Transcript (Including UTRs)
Position: hg19 chr4:6,784,454-6,885,891 Size: 101,438 Total Exon Count: 10 Strand: +
Coding Region
Position: hg19 chr4:6,826,181-6,882,693 Size: 56,513 Coding Exon Count: 8

Page Index	Sequence and Links	UniProtKB Comments	Primers	CTD	Gene Alleles
RNA-Seq Expression	Microarray Expression	RNA Structure	Protein Structure	Other Species	GO Annotations
mRNA Descriptions	Other Names	Model Information	Methods

Data last updated at UCSC: 2024-08-22 23:36:26

Sequence and Links to Tools and Databases

Genomic Sequence (chr4:6,784,454-6,885,891)			mRNA (may differ from genome)		Protein (1395 aa)
Gene Sorter	Genome Browser	Other Species FASTA	VisiGene	Gene interactions	Table Schema
AlphaFold	BioGPS	Ensembl	Entrez Gene	ExonPrimer	GeneCards
HGNC	MGI	PubMed	UniProtKB	BioGrid CRISPR DB

Comments and Description Text from UniProtKB


	ID: K0232_HUMAN DESCRIPTION: RecName: Full=Uncharacterized protein KIAA0232; SEQUENCE CAUTION: Sequence=BAA13221.3; Type=Erroneous initiation; Note=Translation N-terminally shortened;

Primer design for this transcript

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3

Comparative Toxicogenomics Database (CTD)


	The following chemicals interact with this gene D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide D019327 Copper Sulfate

Common Gene Haplotype Alleles


	Press "+" in the title bar above to open this section.

RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)


	Highest median expression: 14.12 RPKM in Brain - Cerebellar Hemisphere Total median expression: 424.87 RPKM View in GTEx track of Genome Browser View at GTEx portal View GTEx Body Map

Microarray Expression Data


	Press "+" in the title bar above to open this section.

mRNA Secondary Structure of 3' and 5' UTRs

Region	Fold Energy	Bases	Energy/Base	Display As
5' UTR	-155.90	468	-0.333	Picture	PostScript	Text
3' UTR	-927.50	3198	-0.290	Picture	PostScript	Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

Protein Domain and Structure Information

Pfam Domains:
PF15376 - Domain of unknown function (DUF4603)

ModBase Predicted Comparative 3D Structure on Q92628


Front	Top	Side

The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

Orthologous Genes in Other Species

Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.

Mouse	Rat	Zebrafish	D. melanogaster	C. elegans	S. cerevisiae
No ortholog	No ortholog	No ortholog	No ortholog	No ortholog	No ortholog
Gene Details	Gene Details
Gene Sorter	Gene Sorter
	RGD

Gene Ontology (GO) Annotations with Structured Vocabulary


	Molecular Function: GO:0000166 nucleotide binding GO:0005524 ATP binding

Descriptions from all associated GenBank mRNAs


	D86985 - Homo sapiens KIAA0232 mRNA for KIAA0232 protein. BC150286 - Homo sapiens KIAA0232, mRNA (cDNA clone MGC:166909 IMAGE:8860111), complete cds. AK124715 - Homo sapiens cDNA FLJ42725 fis, clone BRAWH2001424. EF553521 - Homo sapiens clone DKFZp686E178 KIAA0232 (KIAA0232) mRNA, complete cds. JD404739 - Sequence 385763 from Patent EP1572962. JD464966 - Sequence 445990 from Patent EP1572962. JD389872 - Sequence 370896 from Patent EP1572962. JD129059 - Sequence 110083 from Patent EP1572962. JD378866 - Sequence 359890 from Patent EP1572962. JD377923 - Sequence 358947 from Patent EP1572962. JD511763 - Sequence 492787 from Patent EP1572962. JD541194 - Sequence 522218 from Patent EP1572962. JD039870 - Sequence 20894 from Patent EP1572962. AB385298 - Synthetic construct DNA, clone: pF1KA0232, Homo sapiens KIAA0232 gene for KIAA0232 protein, complete cds, without stop codon, in Flexi system. KJ898089 - Synthetic construct Homo sapiens clone ccsbBroadEn_07483 KIAA0232 gene, encodes complete protein. JD501241 - Sequence 482265 from Patent EP1572962. JD093177 - Sequence 74201 from Patent EP1572962. JD089167 - Sequence 70191 from Patent EP1572962. JD433581 - Sequence 414605 from Patent EP1572962. JD454194 - Sequence 435218 from Patent EP1572962. JD213818 - Sequence 194842 from Patent EP1572962. JD170402 - Sequence 151426 from Patent EP1572962. JD196156 - Sequence 177180 from Patent EP1572962. JD353867 - Sequence 334891 from Patent EP1572962. JD048395 - Sequence 29419 from Patent EP1572962. JD314489 - Sequence 295513 from Patent EP1572962. JD520459 - Sequence 501483 from Patent EP1572962. JD281916 - Sequence 262940 from Patent EP1572962. JD115096 - Sequence 96120 from Patent EP1572962. JD179460 - Sequence 160484 from Patent EP1572962. JD338856 - Sequence 319880 from Patent EP1572962. JD198922 - Sequence 179946 from Patent EP1572962. JD487815 - Sequence 468839 from Patent EP1572962. JD139407 - Sequence 120431 from Patent EP1572962. JD414016 - Sequence 395040 from Patent EP1572962. JD495184 - Sequence 476208 from Patent EP1572962. JD094758 - Sequence 75782 from Patent EP1572962. JD064414 - Sequence 45438 from Patent EP1572962. JD510769 - Sequence 491793 from Patent EP1572962. JD419761 - Sequence 400785 from Patent EP1572962. JD530541 - Sequence 511565 from Patent EP1572962. JD224397 - Sequence 205421 from Patent EP1572962. JD248792 - Sequence 229816 from Patent EP1572962. JD303694 - Sequence 284718 from Patent EP1572962. JD113994 - Sequence 95018 from Patent EP1572962. AF143884 - Homo sapiens clone IMAGE:121558 mRNA sequence. JD047235 - Sequence 28259 from Patent EP1572962. JD336781 - Sequence 317805 from Patent EP1572962. CR457160 - Homo sapiens full open reading frame cDNA clone RZPDo834B058D for gene KIAA0232, KIAA0232 gene product; complete cds, incl. stopcodon. JD376587 - Sequence 357611 from Patent EP1572962. JD549329 - Sequence 530353 from Patent EP1572962. JD503492 - Sequence 484516 from Patent EP1572962. JD166797 - Sequence 147821 from Patent EP1572962. JD509467 - Sequence 490491 from Patent EP1572962. JD248453 - Sequence 229477 from Patent EP1572962. JD299137 - Sequence 280161 from Patent EP1572962.

Other Names for This Gene


	Alternate Gene Symbols: A7E2D2, ENST00000307659.1, ENST00000307659.2, ENST00000307659.3, ENST00000307659.4, ENST00000307659.5, K0232_HUMAN, NM_014743, Q92628, uc317ocx.1, uc317ocx.2 UCSC ID: ENST00000307659.6_4 RefSeq Accession: NM_014743.3 Protein: Q92628 (aka K0232_HUMAN)

Gene Model Information


	Click here for a detailed description of the fields of the table above.

Methods, Credits, and Use Restrictions


	Click here for details on how this gene model was made and data restrictions if any.