The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on G3XAA4
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0046872 metal ion binding GO:0061630 ubiquitin protein ligase activity
Biological Process: GO:0000209 protein polyubiquitination GO:0050767 regulation of neurogenesis GO:0050769 positive regulation of neurogenesis GO:0051865 protein autoubiquitination GO:0060395 SMAD protein signal transduction GO:1990138 neuron projection extension
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
