ID:FBX46_HUMAN DESCRIPTION: RecName: Full=F-box only protein 46; AltName: Full=F-box only protein 34-like; FUNCTION: Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex (By similarity). SUBUNIT: Interacts with SKP1 and CUL1 (By similarity). INTERACTION: P63208:SKP1; NbExp=3; IntAct=EBI-2322982, EBI-307486; SIMILARITY: Contains 1 F-box domain. CAUTION: The region from 1 to 163 was deduced from the genomic sequence and ESTs by similarity to the mouse sequence. SEQUENCE CAUTION: Sequence=AAH21978.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=AAH21978.1; Type=Erroneous termination; Positions=604; Note=Translated as stop;
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q6PJ61
Front
Top
Side
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.