ID:FBLL1_HUMAN DESCRIPTION: RecName: Full=rRNA/tRNA 2'-O-methyltransferase fibrillarin-like protein 1; EC=2.1.1.-; FUNCTION: Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'- hydroxyl methylation of ribose moieties in pre-ribosomal RNA (By similarity). SUBCELLULAR LOCATION: Nucleus, nucleolus. Note=Fibrillar region of the nucleolus (By similarity). PTM: By homology to other fibrillarins, some or all of the N- terminal domain arginines are modified to asymmetric dimethylarginine (DMA). SIMILARITY: Belongs to the methyltransferase superfamily. Fibrillarin family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on A6NHQ2
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
