ID:SGT1_HUMAN DESCRIPTION: RecName: Full=Protein SGT1; Short=hSGT1; AltName: Full=Protein ecdysoneless homolog; AltName: Full=Suppressor of GCR2; FUNCTION: Novel regulator of p53 stability and function. May also be a transcriptional activator required for the expression of glycolytic genes. SUBUNIT: Interacts with TP53 and MDM2. SUBCELLULAR LOCATION: Cytoplasm. Nucleus. TISSUE SPECIFICITY: Highly expressed in muscle and heart. SIMILARITY: Belongs to the SGT1 family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on O95905
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0006110 regulation of glycolytic process GO:0006351 transcription, DNA-templated GO:0006355 regulation of transcription, DNA-templated GO:0006366 transcription from RNA polymerase II promoter GO:0006397 mRNA processing GO:0008283 cell proliferation GO:0008380 RNA splicing GO:0045944 positive regulation of transcription from RNA polymerase II promoter GO:2000045 regulation of G1/S transition of mitotic cell cycle
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Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
