ID:DDX28_HUMAN DESCRIPTION: RecName: Full=Probable ATP-dependent RNA helicase DDX28; EC=3.6.4.13; AltName: Full=Mitochondrial DEAD box protein 28; FUNCTION: May be involved in RNA processing or transport. Has RNA and Mg(2+)-dependent ATPase activity. CATALYTIC ACTIVITY: ATP + H(2)O = ADP + phosphate. SUBCELLULAR LOCATION: Nucleus. Mitochondrion. Note=Transported between these two compartments. Nuclear localization depends on active RNA polymerase II transcription. TISSUE SPECIFICITY: Expressed in all tissues tested, including brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, leukocytes, colon, small intestine, ovary and prostate. SIMILARITY: Belongs to the DEAD box helicase family. SIMILARITY: Contains 1 helicase ATP-binding domain. SIMILARITY: Contains 1 helicase C-terminal domain.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9NUL7
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.