The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on O00399
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Biological Process: GO:0006888 ER to Golgi vesicle-mediated transport GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II
D84145 - Homo sapiens WS-3 mRNA, complete cds. AK314128 - Homo sapiens cDNA, FLJ94825, Homo sapiens dynactin 6 (DCTN6), mRNA. BC013175 - Homo sapiens dynactin 6, mRNA (cDNA clone MGC:8931 IMAGE:3925231), complete cds. HQ448326 - Synthetic construct Homo sapiens clone IMAGE:100071744; CCSB000858_04 dynactin 6 (DCTN6) gene, encodes complete protein. KJ893107 - Synthetic construct Homo sapiens clone ccsbBroadEn_02501 DCTN6 gene, encodes complete protein. CR456851 - Homo sapiens full open reading frame cDNA clone RZPDo834G086D for gene DCTN6, dynactin 6; complete cds, incl. stopcodon. JD040670 - Sequence 21694 from Patent EP1572962. JD307719 - Sequence 288743 from Patent EP1572962. JD082304 - Sequence 63328 from Patent EP1572962.
Biochemical and Signaling Pathways
BioCarta from NCI Cancer Genome Anatomy Project h_Lis1Pathway - Lissencephaly gene (LIS1) in neuronal migration and development
Reactome (by CSHL, EBI, and GO)
Protein O00399 (Reactome details) participates in the following event(s):
R-HSA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin R-HSA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex R-HSA-8849350 RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex R-HSA-2132295 MHC class II antigen presentation R-HSA-6807878 COPI-mediated anterograde transport R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic R-HSA-1280218 Adaptive Immune System R-HSA-199977 ER to Golgi Anterograde Transport R-HSA-8856688 Golgi-to-ER retrograde transport R-HSA-168256 Immune System R-HSA-199991 Membrane Trafficking R-HSA-948021 Transport to the Golgi and subsequent modification R-HSA-6811442 Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-5653656 Vesicle-mediated transport R-HSA-446203 Asparagine N-linked glycosylation R-HSA-597592 Post-translational protein modification R-HSA-392499 Metabolism of proteins
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
