Human Gene DCK (ENST00000286648.10_4) from GENCODE V47lift37
  Description: deoxycytidine kinase (from RefSeq NM_000788.3)
Gencode Transcript: ENST00000286648.10_4
Gencode Gene: ENSG00000156136.10_11
Transcript (Including UTRs)
   Position: hg19 chr4:71,859,366-71,896,631 Size: 37,266 Total Exon Count: 7 Strand: +
Coding Region
   Position: hg19 chr4:71,859,553-71,895,095 Size: 35,543 Coding Exon Count: 7 

Page IndexSequence and LinksUniProtKB CommentsPrimersMalaCardsCTD
Gene AllelesRNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther Species
GO AnnotationsmRNA DescriptionsPathwaysOther NamesModel InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr4:71,859,366-71,896,631)mRNA (may differ from genome)Protein (260 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCMalacardsMGIOMIMPubMedReactome
UniProtKBWikipediaBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: DCK_HUMAN
DESCRIPTION: RecName: Full=Deoxycytidine kinase; Short=dCK; EC=2.7.1.74;
FUNCTION: Required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG) and deoxyadenosine (dA). Has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. It is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and chemotherapeutic agents.
CATALYTIC ACTIVITY: NTP + deoxycytidine = NDP + dCMP.
BIOPHYSICOCHEMICAL PROPERTIES: Kinetic parameters: KM=6.2 uM for deoxycytidine (dC); KM=15.5 uM for cytarabine (araC); KM=22 uM for gemcitabine (dC);
SUBUNIT: Homodimer.
SUBCELLULAR LOCATION: Nucleus.
PTM: Phosphorylated upon DNA damage, probably by ATM or ATR (By similarity). Phosphorylated and activated in vitro upon phosphorylation at Ser-74 by CSNK1D/CK1.
SIMILARITY: Belongs to the DCK/DGK family.
CAUTION: Was shown to be phosphorylated and activated by CSNK1D/CK1 in vitro but probably not in vivo (PubMed:20637175).

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  MalaCards Disease Associations
  MalaCards Gene Search: DCK
Diseases sorted by gene-association score: periampullary adenocarcinoma (16), neurofibrosarcoma (11), uterine sarcoma (7), chronic lymphocytic leukemia (4), pancreatic cancer (4), lung cancer (3), hematologic cancer (2), leukemia, acute myeloid (1)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 12.86 RPKM in Spleen
Total median expression: 272.54 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -74.50187-0.398 Picture PostScript Text
3' UTR -303.901536-0.198 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR002624 - Deoxynucleoside_kinase

Pfam Domains:
PF01712 - Deoxynucleoside kinase

SCOP Domains:
50729 - PH domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases

Protein Data Bank (PDB) 3-D Structure
MuPIT help
1P5Z - X-ray MuPIT 1P60 - X-ray MuPIT 1P61 - X-ray MuPIT 1P62 - X-ray 2A2Z - X-ray MuPIT 2A30 - X-ray MuPIT 2A7Q - X-ray MuPIT 2NO0 - X-ray MuPIT 2NO1 - X-ray MuPIT 2NO6 - X-ray MuPIT 2NO7 - X-ray MuPIT 2NO9 - X-ray MuPIT 2NOA - X-ray MuPIT 2QRN - X-ray MuPIT 2QRO - X-ray MuPIT 2ZI3 - X-ray MuPIT 2ZI4 - X-ray MuPIT 2ZI5 - X-ray MuPIT 2ZI6 - X-ray MuPIT 2ZI7 - X-ray MuPIT 2ZI9 - X-ray MuPIT 2ZIA - X-ray MuPIT 3HP1 - X-ray MuPIT 3IPX - X-ray 3IPY - X-ray 3KFX - X-ray MuPIT 3MJR - X-ray MuPIT 3QEJ - X-ray MuPIT 3QEN - X-ray MuPIT 3QEO - X-ray MuPIT


ModBase Predicted Comparative 3D Structure on P27707
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGDEnsembl   
      
      

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0000166 nucleotide binding
GO:0004137 deoxycytidine kinase activity
GO:0005524 ATP binding
GO:0008144 drug binding
GO:0016301 kinase activity
GO:0016740 transferase activity
GO:0019206 nucleoside kinase activity
GO:0042803 protein homodimerization activity

Biological Process:
GO:0006139 nucleobase-containing compound metabolic process
GO:0006220 pyrimidine nucleotide metabolic process
GO:0009157 deoxyribonucleoside monophosphate biosynthetic process
GO:0009165 nucleotide biosynthetic process
GO:0016310 phosphorylation
GO:0043097 pyrimidine nucleoside salvage
GO:0043101 purine-containing compound salvage

Cellular Component:
GO:0005634 nucleus
GO:0005829 cytosol


-  Descriptions from all associated GenBank mRNAs
  AK303292 - Homo sapiens cDNA FLJ51425 complete cds, highly similar to Deoxycytidine kinase (EC 2.7.1.74).
AK313523 - Homo sapiens cDNA, FLJ94081, Homo sapiens deoxycytidine kinase (DCK), mRNA.
JD024804 - Sequence 5828 from Patent EP1572962.
BC103764 - Homo sapiens deoxycytidine kinase, mRNA (cDNA clone MGC:117410 IMAGE:6472612), complete cds.
JD036186 - Sequence 17210 from Patent EP1572962.
M60527 - Human deoxycytidine kinase mRNA, complete cds.
BC114617 - Homo sapiens deoxycytidine kinase, mRNA (cDNA clone MGC:138632 IMAGE:40032871), complete cds.
JD415546 - Sequence 396570 from Patent EP1572962.
JF806429 - Homo sapiens deoxynucleoside kinase mRNA, complete cds.
CR541876 - Homo sapiens full open reading frame cDNA clone RZPDo834D0233D for gene DCK, deoxycytidine kinase; complete cds, without stopcodon.
BT019941 - Homo sapiens deoxycytidine kinase mRNA, complete cds.
BT019942 - Homo sapiens deoxycytidine kinase mRNA, complete cds.
KJ891031 - Synthetic construct Homo sapiens clone ccsbBroadEn_00425 DCK gene, encodes complete protein.
KJ896691 - Synthetic construct Homo sapiens clone ccsbBroadEn_06085 DCK gene, encodes complete protein.
KR711858 - Synthetic construct Homo sapiens clone CCSBHm_00031396 DCK (DCK) mRNA, encodes complete protein.
KR711859 - Synthetic construct Homo sapiens clone CCSBHm_00031397 DCK (DCK) mRNA, encodes complete protein.
KR711860 - Synthetic construct Homo sapiens clone CCSBHm_00031398 DCK (DCK) mRNA, encodes complete protein.
CR536527 - Homo sapiens full open reading frame cDNA clone RZPDo834F0322D for gene DCK, deoxycytidine kinase; complete cds, incl. stopcodon.
JD474624 - Sequence 455648 from Patent EP1572962.
JD546878 - Sequence 527902 from Patent EP1572962.
JD280364 - Sequence 261388 from Patent EP1572962.
JD563628 - Sequence 544652 from Patent EP1572962.
JD316993 - Sequence 298017 from Patent EP1572962.
JD313861 - Sequence 294885 from Patent EP1572962.
JD509015 - Sequence 490039 from Patent EP1572962.
JD566636 - Sequence 547660 from Patent EP1572962.
JD279797 - Sequence 260821 from Patent EP1572962.
JD185586 - Sequence 166610 from Patent EP1572962.
MA873464 - JP 2018536436-A/5300: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873465 - JP 2018536436-A/5301: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873466 - JP 2018536436-A/5302: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873468 - JP 2018536436-A/5304: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873469 - JP 2018536436-A/5305: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873470 - JP 2018536436-A/5306: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873471 - JP 2018536436-A/5307: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873472 - JP 2018536436-A/5308: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873473 - JP 2018536436-A/5309: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873474 - JP 2018536436-A/5310: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873475 - JP 2018536436-A/5311: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873476 - JP 2018536436-A/5312: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873477 - JP 2018536436-A/5313: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
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MA873479 - JP 2018536436-A/5315: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
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MA873484 - JP 2018536436-A/5320: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873485 - JP 2018536436-A/5321: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873486 - JP 2018536436-A/5322: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873544 - JP 2018536436-A/5380: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873545 - JP 2018536436-A/5381: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873546 - JP 2018536436-A/5382: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873547 - JP 2018536436-A/5383: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873548 - JP 2018536436-A/5384: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873555 - JP 2018536436-A/5391: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873556 - JP 2018536436-A/5392: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873557 - JP 2018536436-A/5393: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873558 - JP 2018536436-A/5394: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873559 - JP 2018536436-A/5395: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873560 - JP 2018536436-A/5396: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873568 - JP 2018536436-A/5404: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873569 - JP 2018536436-A/5405: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873570 - JP 2018536436-A/5406: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873571 - JP 2018536436-A/5407: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873572 - JP 2018536436-A/5408: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873573 - JP 2018536436-A/5409: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
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MA873580 - JP 2018536436-A/5416: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
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MA873582 - JP 2018536436-A/5418: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873583 - JP 2018536436-A/5419: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873584 - JP 2018536436-A/5420: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873585 - JP 2018536436-A/5421: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873589 - JP 2018536436-A/5425: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873590 - JP 2018536436-A/5426: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873591 - JP 2018536436-A/5427: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873592 - JP 2018536436-A/5428: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873595 - JP 2018536436-A/5431: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873596 - JP 2018536436-A/5432: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
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MA873600 - JP 2018536436-A/5436: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
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MA873604 - JP 2018536436-A/5440: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
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MA873607 - JP 2018536436-A/5443: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873609 - JP 2018536436-A/5445: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873613 - JP 2018536436-A/5449: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873614 - JP 2018536436-A/5450: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873615 - JP 2018536436-A/5451: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873617 - JP 2018536436-A/5453: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
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MA873620 - JP 2018536436-A/5456: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
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LY595881 - KR 1020180133840-A/5305: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595882 - KR 1020180133840-A/5306: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595883 - KR 1020180133840-A/5307: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595884 - KR 1020180133840-A/5308: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595885 - KR 1020180133840-A/5309: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595886 - KR 1020180133840-A/5310: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595887 - KR 1020180133840-A/5311: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
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LY595889 - KR 1020180133840-A/5313: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595890 - KR 1020180133840-A/5314: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595891 - KR 1020180133840-A/5315: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595892 - KR 1020180133840-A/5316: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
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LY595894 - KR 1020180133840-A/5318: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
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LY595896 - KR 1020180133840-A/5320: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595897 - KR 1020180133840-A/5321: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595898 - KR 1020180133840-A/5322: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595956 - KR 1020180133840-A/5380: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595957 - KR 1020180133840-A/5381: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595958 - KR 1020180133840-A/5382: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595959 - KR 1020180133840-A/5383: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595960 - KR 1020180133840-A/5384: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595967 - KR 1020180133840-A/5391: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595968 - KR 1020180133840-A/5392: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595969 - KR 1020180133840-A/5393: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595970 - KR 1020180133840-A/5394: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595971 - KR 1020180133840-A/5395: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595972 - KR 1020180133840-A/5396: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595980 - KR 1020180133840-A/5404: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595981 - KR 1020180133840-A/5405: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595982 - KR 1020180133840-A/5406: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595983 - KR 1020180133840-A/5407: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595984 - KR 1020180133840-A/5408: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595985 - KR 1020180133840-A/5409: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595986 - KR 1020180133840-A/5410: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595992 - KR 1020180133840-A/5416: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595993 - KR 1020180133840-A/5417: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595994 - KR 1020180133840-A/5418: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595995 - KR 1020180133840-A/5419: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595996 - KR 1020180133840-A/5420: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595997 - KR 1020180133840-A/5421: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY596001 - KR 1020180133840-A/5425: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
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LY596007 - KR 1020180133840-A/5431: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY596008 - KR 1020180133840-A/5432: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY596009 - KR 1020180133840-A/5433: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY596010 - KR 1020180133840-A/5434: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
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LY596012 - KR 1020180133840-A/5436: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY596013 - KR 1020180133840-A/5437: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY596014 - KR 1020180133840-A/5438: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY596015 - KR 1020180133840-A/5439: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY596016 - KR 1020180133840-A/5440: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY596017 - KR 1020180133840-A/5441: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY596018 - KR 1020180133840-A/5442: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY596019 - KR 1020180133840-A/5443: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY596021 - KR 1020180133840-A/5445: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY596025 - KR 1020180133840-A/5449: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY596026 - KR 1020180133840-A/5450: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY596027 - KR 1020180133840-A/5451: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY596029 - KR 1020180133840-A/5453: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY596030 - KR 1020180133840-A/5454: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY596031 - KR 1020180133840-A/5455: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY596032 - KR 1020180133840-A/5456: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.

-  Biochemical and Signaling Pathways
  BioCyc Knowledge Library
PWY-7199 - pyrimidine deoxyribonucleosides salvage
PWY-7200 - superpathway of pyrimidine deoxyribonucleoside salvage
PWY-7224 - purine deoxyribonucleosides salvage

Reactome (by CSHL, EBI, and GO)

Protein P27707 (Reactome details) participates in the following event(s):

R-HSA-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK)
R-HSA-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK)
R-HSA-73614 Pyrimidine salvage
R-HSA-74217 Purine salvage
R-HSA-8956321 Nucleotide salvage
R-HSA-15869 Metabolism of nucleotides
R-HSA-1430728 Metabolism

-  Other Names for This Gene
  Alternate Gene Symbols: B2R8V6, DCK_HUMAN, ENST00000286648.1, ENST00000286648.2, ENST00000286648.3, ENST00000286648.4, ENST00000286648.5, ENST00000286648.6, ENST00000286648.7, ENST00000286648.8, ENST00000286648.9, NM_000788, P27707, Q5TZY7, Q6FI11, uc317kks.1, uc317kks.2
UCSC ID: ENST00000286648.10_4
RefSeq Accession: NM_000788.3
Protein: P27707 (aka DCK_HUMAN)

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.