ID:CLGN_HUMAN DESCRIPTION: RecName: Full=Calmegin; Flags: Precursor; FUNCTION: Probably plays an important role in spermatogenesis. Binds calcium ions. SUBUNIT: Interacts with PDILT. SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Single-pass type I membrane protein. TISSUE SPECIFICITY: Testis. SIMILARITY: Belongs to the calreticulin family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on O14967
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0005509 calcium ion binding GO:0044183 protein binding involved in protein folding GO:0051082 unfolded protein binding
Biological Process: GO:0006457 protein folding GO:0007338 single fertilization GO:0007339 binding of sperm to zona pellucida GO:0065003 macromolecular complex assembly