Human Gene CCDC7 (ENST00000639629.2_11) from GENCODE V47lift37
  Description: coiled-coil domain containing 7, transcript variant 6 (from RefSeq NM_001395015.1)
Gencode Transcript: ENST00000639629.2_11
Gencode Gene: ENSG00000216937.14_20
Transcript (Including UTRs)
   Position: hg19 chr10:32,735,068-33,171,792 Size: 436,725 Total Exon Count: 44 Strand: +
Coding Region
   Position: hg19 chr10:32,740,571-33,165,321 Size: 424,751 Coding Exon Count: 42 

Page IndexSequence and LinksUniProtKB CommentsPrimersGene AllelesMicroarray Expression
RNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Methods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr10:32,735,068-33,171,792)mRNA (may differ from genome)Protein (1385 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblExonPrimerGeneCardsHGNC
MGIPubMedUniProtKB

-  Comments and Description Text from UniProtKB
  ID: CCDC7_HUMAN
DESCRIPTION: RecName: Full=Coiled-coil domain-containing protein 7; AltName: Full=Protein BIOT2;
FUNCTION: May play a role in tumorigenesis (By similarity).
TISSUE SPECIFICITY: Expressed in epithelium of normal cervix and cervical cancer. Overexpressed in early and interim cervical cancer.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


+  Common Gene Haplotype Alleles
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+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -114.00309-0.369 Picture PostScript Text
3' UTR -81.90359-0.228 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  Pfam Domains:
PF15368 - Spermatogenesis family BioT2

ModBase Predicted Comparative 3D Structure on Q96M83
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-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
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-  Descriptions from all associated GenBank mRNAs
  AK057324 - Homo sapiens cDNA FLJ32762 fis, clone TESTI2001826.
BC042672 - Homo sapiens coiled-coil domain containing 7, mRNA (cDNA clone MGC:35087 IMAGE:5166976), complete cds.
BC022020 - Homo sapiens coiled-coil domain containing 7, mRNA (cDNA clone MGC:26635 IMAGE:4825109), complete cds.
GQ891461 - Homo sapiens clone HEL-S-182 epididymis secretory sperm binding protein mRNA, complete cds.
BX647771 - Homo sapiens mRNA; cDNA DKFZp686N0559 (from clone DKFZp686N0559).
EF656618 - Homo sapiens BioT2-A mRNA, complete cds, alternatively spliced.
EF656619 - Homo sapiens BioT2-B mRNA, complete cds, alternatively spliced.
EF656620 - Homo sapiens BioT2-C mRNA, complete cds, alternatively spliced.
KJ895853 - Synthetic construct Homo sapiens clone ccsbBroadEn_05247 CCDC7 gene, encodes complete protein.
CU692458 - Synthetic construct Homo sapiens gateway clone IMAGE:100019628 5' read CCDC7 mRNA.
AK058148 - Homo sapiens cDNA FLJ25419 fis, clone TST03533.
AK023093 - Homo sapiens cDNA FLJ13031 fis, clone NT2RP3001113, weakly similar to INTRACELLULAR PROTEIN TRANSPORT PROTEIN USO1.
BC125090 - Homo sapiens chromosome 10 open reading frame 68, mRNA (cDNA clone MGC:149766 IMAGE:40118176), complete cds.
BC125091 - Homo sapiens chromosome 10 open reading frame 68, mRNA (cDNA clone MGC:149767 IMAGE:40118177), complete cds.
AK301824 - Homo sapiens cDNA FLJ56261 complete cds.
AK097668 - Homo sapiens cDNA FLJ40349 fis, clone TESTI2033395.
JD360259 - Sequence 341283 from Patent EP1572962.
JD503967 - Sequence 484991 from Patent EP1572962.
JD363449 - Sequence 344473 from Patent EP1572962.
JD359253 - Sequence 340277 from Patent EP1572962.
JD113831 - Sequence 94855 from Patent EP1572962.
JD059295 - Sequence 40319 from Patent EP1572962.
JD235465 - Sequence 216489 from Patent EP1572962.
JD553985 - Sequence 535009 from Patent EP1572962.
JD084492 - Sequence 65516 from Patent EP1572962.
JD374979 - Sequence 356003 from Patent EP1572962.
JD365204 - Sequence 346228 from Patent EP1572962.
BX537995 - Homo sapiens mRNA; cDNA DKFZp686F0730 (from clone DKFZp686F0730).
JD358438 - Sequence 339462 from Patent EP1572962.
JD405411 - Sequence 386435 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: B0QZ71, BIOT2, C10orf68, CCDC7_HUMAN, ENST00000639629.1, NM_001395015, Q08AN7, Q5VW55, Q8IVQ0, Q8N7T7, Q8NEQ0, Q96M83, Q9H943, uc328fud.1, uc328fud.2
UCSC ID: ENST00000639629.2_11
RefSeq Accession: NM_001395015.1
Protein: Q96M83 (aka CCDC7_HUMAN or CCD7_HUMAN)

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.