ID:BICD1_HUMAN DESCRIPTION: RecName: Full=Protein bicaudal D homolog 1; Short=Bic-D 1; FUNCTION: Regulates coat complex coatomer protein I (COPI)- independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex. SUBUNIT: Interacts with RAB6A. Interacts (via C-terminus) with RAB6B (GTP-bound); the interaction is direct. Interacts with CLIP- 115 and KIFC2 (By similarity). Interacts with human cytomegalovirus/HHV-5 protein UL32. INTERACTION: P40763:STAT3; NbExp=2; IntAct=EBI-1104509, EBI-518675; SUBCELLULAR LOCATION: Golgi apparatus. TISSUE SPECIFICITY: Expressed in the brain, heart and skeletal muscle. PTM: Isoform 3 is phosphorylated on Ser-865 and Thr-866. SIMILARITY: Belongs to the BicD family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF09730 - Microtubule-associated protein Bicaudal-D
SCOP Domains: 100939 - SPOC domain-like 58010 - Fibrinogen coiled-coil and central regions
ModBase Predicted Comparative 3D Structure on Q96G01
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
