ID:AOAH_HUMAN DESCRIPTION: RecName: Full=Acyloxyacyl hydrolase; EC=3.1.1.77; Contains: RecName: Full=Acyloxyacyl hydrolase small subunit; Contains: RecName: Full=Acyloxyacyl hydrolase large subunit; Flags: Precursor; FUNCTION: Removes the secondary (acyloxyacyl-linked) fatty acyl chains from the lipid A region of bacterial lipopolysaccharides. CATALYTIC ACTIVITY: 3-(acyloxy)acyl group of bacterial toxin = 3- hydroxyacyl group of bacterial toxin + a fatty acid. SUBUNIT: Heterodimer. SUBCELLULAR LOCATION: Secreted. PTM: Both subunits contain a number of cysteine residues that may form disulfide bridges. SIMILARITY: Contains 1 saposin B-type domain.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on P28039
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
